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Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype

BACKGROUND: Leucine-rich repeat kinase 2 (LRRK2) is a common gene implicated in Parkinson’s disease (PD) and is also thought to be fundamentally involved in numerous immune functions. Thus, we assessed the role of LRRK2 in the context of the effects of the environmental toxicant, paraquat, that has...

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Bibliografiska uppgifter
I publikationen:J Neuroinflammation
Huvudupphovsmän: Rudyk, Chris, Dwyer, Zach, Hayley, Shawn
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554960/
https://ncbi.nlm.nih.gov/pubmed/31174552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1483-7
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