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Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

Parkinson's disease (PD) is a disorder of movement, cognition, and emotion, and it is characterized pathologically by neuronal degeneration with Lewy bodies, which are cytoplasmic inclusion bodies containing deposits of aggregated proteins. Most PD cases appear to be sporadic, but genetic forms...

詳細記述

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書誌詳細
主要な著者: Smith, Wanli W., Pei, Zhong, Jiang, Haibing, Moore, Darren J., Liang, Yideng, West, Andrew B., Dawson, Valina L., Dawson, Ted M., Ross, Christopher A.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317945/
https://ncbi.nlm.nih.gov/pubmed/16352719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508052102
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