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Reevaluation of Phosphorylation Sites in the Parkinson Disease-associated Leucine-rich Repeat Kinase 2

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been identified as an important cause of late-onset, autosomal dominant familial Parkinson disease and contribute to sporadic Parkinson disease. LRRK2 is a large complex protein with multiple functional domains, including a Roc-GTPase,...

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Detalhes bibliográficos
Main Authors: Li, Xiaojie, Moore, Darren J., Xiong, Yulan, Dawson, Ted M., Dawson, Valina L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937988/
https://ncbi.nlm.nih.gov/pubmed/20595391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127639
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