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Leucine rich repeat kinase 2 (LRRK2) as a potential therapeutic target for Parkinson’s disease
Parkinson’s disease (PD) is caused by the progressive degeneration of dopaminergic neurons in the substantia nigra. Although the etiology for most PD remains elusive, the identification of specific genetic defects in familial cases of PD and the signaling pathways governed by these genes has provide...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383378/ https://ncbi.nlm.nih.gov/pubmed/22578536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2012.04.001 |
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