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Leucine rich repeat kinase 2 (LRRK2) as a potential therapeutic target for Parkinson’s disease

Parkinson’s disease (PD) is caused by the progressive degeneration of dopaminergic neurons in the substantia nigra. Although the etiology for most PD remains elusive, the identification of specific genetic defects in familial cases of PD and the signaling pathways governed by these genes has provide...

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Autori principali: Lee, Byoung Dae, Dawson, Valina L., Dawson, Ted M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383378/
https://ncbi.nlm.nih.gov/pubmed/22578536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2012.04.001
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