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Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype

BACKGROUND: Leucine-rich repeat kinase 2 (LRRK2) is a common gene implicated in Parkinson’s disease (PD) and is also thought to be fundamentally involved in numerous immune functions. Thus, we assessed the role of LRRK2 in the context of the effects of the environmental toxicant, paraquat, that has...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Rudyk, Chris, Dwyer, Zach, Hayley, Shawn
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554960/
https://ncbi.nlm.nih.gov/pubmed/31174552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1483-7
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