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Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype

BACKGROUND: Leucine-rich repeat kinase 2 (LRRK2) is a common gene implicated in Parkinson’s disease (PD) and is also thought to be fundamentally involved in numerous immune functions. Thus, we assessed the role of LRRK2 in the context of the effects of the environmental toxicant, paraquat, that has...

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Bibliografske podrobnosti
izdano v:J Neuroinflammation
Main Authors: Rudyk, Chris, Dwyer, Zach, Hayley, Shawn
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554960/
https://ncbi.nlm.nih.gov/pubmed/31174552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1483-7
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