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The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson’s disease
Parkinson’s disease, like many other common age-related conditions, is now recognized to have a substantial genetic component. Here, I will discuss how mutations in a large complex gene, LRRK2, affect protein function and review recent evidence that LRRK2 mutations affect pathways that involve other...
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| Опубликовано в: : | Nat Rev Neurosci |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4662256/ https://ncbi.nlm.nih.gov/pubmed/21088684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn2935 |
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