OR24-4 Homeostatic and Tumourigenic Activity of SOX2+ Pituitary Stem Cells is Controlled by the LATS/YAP/TAZ Cascade

SOX2 positive pituitary stem cells (PSCs) are specified during embryonic development and persist throughout life, giving rise to all anterior pituitary endocrine lineages. We have previously revealed the activation of the LATS/YAP/TAZ signaling cascade in the developing and postnatal mammalian pitui...

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Опубликовано в: :J Endocr Soc
Главные авторы: Lodge, Emily, Santambrogio, Alice, Russell, John, Bornstein, Stefan, Andoniadou, Cynthia
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2019
Предметы:
Neuroendocrinology and Pituitary
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554787/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR24-4
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