LATS1 and LATS2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ

In the adult liver, the Hippo pathway kinases MST1/2 and LATS1/2 control activation of the transcriptional coactivators YAP and TAZ in hepatocytes and biliary epithelial cells (BECs) thereby regulating liver cell proliferation, differentiation and malignant transformation. Less is known about the co...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Yi, Jing, Lu, Li, Yanger, Kilangsungla, Wang, Wenqi, Sohn, Bo Hwa, Stanger, Ben Z., Zhang, Min, Martin, James F., Ajani, Jaffer A., Chen, Junjie, Lee, Ju-Seog, Song, Shumei, Johnson, Randy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863546/
https://ncbi.nlm.nih.gov/pubmed/27531557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28768
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