OR24-4 Homeostatic and Tumourigenic Activity of SOX2+ Pituitary Stem Cells is Controlled by the LATS/YAP/TAZ Cascade

SOX2 positive pituitary stem cells (PSCs) are specified during embryonic development and persist throughout life, giving rise to all anterior pituitary endocrine lineages. We have previously revealed the activation of the LATS/YAP/TAZ signaling cascade in the developing and postnatal mammalian pitui...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Endocr Soc
Prif Awduron: Lodge, Emily, Santambrogio, Alice, Russell, John, Bornstein, Stefan, Andoniadou, Cynthia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2019
Pynciau:
Neuroendocrinology and Pituitary
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554787/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR24-4
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