OR24-4 Homeostatic and Tumourigenic Activity of SOX2+ Pituitary Stem Cells is Controlled by the LATS/YAP/TAZ Cascade

SOX2 positive pituitary stem cells (PSCs) are specified during embryonic development and persist throughout life, giving rise to all anterior pituitary endocrine lineages. We have previously revealed the activation of the LATS/YAP/TAZ signaling cascade in the developing and postnatal mammalian pitui...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Lodge, Emily, Santambrogio, Alice, Russell, John, Bornstein, Stefan, Andoniadou, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Neuroendocrinology and Pituitary
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554787/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR24-4
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