OR24-4 Homeostatic and Tumourigenic Activity of SOX2+ Pituitary Stem Cells is Controlled by the LATS/YAP/TAZ Cascade

SOX2 positive pituitary stem cells (PSCs) are specified during embryonic development and persist throughout life, giving rise to all anterior pituitary endocrine lineages. We have previously revealed the activation of the LATS/YAP/TAZ signaling cascade in the developing and postnatal mammalian pitui...

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Bibliografske podrobnosti
izdano v:J Endocr Soc
Main Authors: Lodge, Emily, Santambrogio, Alice, Russell, John, Bornstein, Stefan, Andoniadou, Cynthia
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2019
Teme:
Neuroendocrinology and Pituitary
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554787/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR24-4
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