5-Hydroxymethylcytosine Profiles Are Prognostic of Outcome in Neuroblastoma and Reveal Transcriptional Networks That Correlate With Tumor Phenotype

PURPOSE: Whole-genome profiles of the epigenetic modification 5-hydroxymethylcytosine (5-hmC) are robust diagnostic biomarkers in adult patients with cancer. We investigated if 5-hmC profiles would serve as novel prognostic markers in neuroblastoma, a clinically heterogeneous pediatric cancer. Becau...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:JCO Precis Oncol
Main Authors: Applebaum, Mark A., Barr, Erin K., Karpus, Jason, Nie, Ji, Zhang, Zhou, Armstrong, Amy E., Uppal, Sakshi, Sukhanova, Madina, Zhang, Wei, Chlenski, Alexandre, Salwen, Helen R., Wilkinson, Emma, Dobratic, Marija, Grossman, Robert, Godley, Lucy A., Stranger, Barbara E., He, Chuan, Cohn, Susan L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2019
Fag:
Original Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6553657/
https://ncbi.nlm.nih.gov/pubmed/31179414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.18.00402
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker