Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids

SPARC is a matrix protein that mediates interactions between cells and the microenvironment. In cancer, SPARC may either promote or inhibit tumor growth depending upon the tumor type. In neuroblastoma, SPARC is expressed in the stromal Schwannian cells and functions as a tumor suppressor. Here, we d...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chlenski, Alexandre, Dobratic, Marija, Salwen, Helen R., Applebaum, Mark, Guerrero, Lisa J., Miller, Ryan, DeWane, Gillian, Solomaha, Elena, Marks, Jeremy D., Cohn, Susan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363614/
https://ncbi.nlm.nih.gov/pubmed/27776337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12773
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