Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids

SPARC is a matrix protein that mediates interactions between cells and the microenvironment. In cancer, SPARC may either promote or inhibit tumor growth depending upon the tumor type. In neuroblastoma, SPARC is expressed in the stromal Schwannian cells and functions as a tumor suppressor. Here, we d...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Chlenski, Alexandre, Dobratic, Marija, Salwen, Helen R., Applebaum, Mark, Guerrero, Lisa J., Miller, Ryan, DeWane, Gillian, Solomaha, Elena, Marks, Jeremy D., Cohn, Susan L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363614/
https://ncbi.nlm.nih.gov/pubmed/27776337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12773
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