Secreted protein acidic and rich in cysteine (SPARC) induces lipotoxicity in neuroblastoma by regulating transport of albumin complexed with fatty acids

SPARC is a matrix protein that mediates interactions between cells and the microenvironment. In cancer, SPARC may either promote or inhibit tumor growth depending upon the tumor type. In neuroblastoma, SPARC is expressed in the stromal Schwannian cells and functions as a tumor suppressor. Here, we d...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Chlenski, Alexandre, Dobratic, Marija, Salwen, Helen R., Applebaum, Mark, Guerrero, Lisa J., Miller, Ryan, DeWane, Gillian, Solomaha, Elena, Marks, Jeremy D., Cohn, Susan L.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363614/
https://ncbi.nlm.nih.gov/pubmed/27776337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12773
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