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Pharmacokinetics of artesunate after single oral administration to rats

BACKGROUND: Artesunate is a commonly used antimalarial drug derived from artemisinin. It is rapidly converted to dihydroartemisinin. Little is known on this conversion in the GI tract and blood, and how this influences absorption. In order to study the absorption phase of the kinetics of artesunate...

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Détails bibliographiques
Auteurs principaux: Olliaro, Piero L, Nair, Naren K, Sathasivam, Kathir, Mansor, Sharif M, Navaratnam, Vis
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC65525/
https://ncbi.nlm.nih.gov/pubmed/11835690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-1-12
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