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Pharmacokinetics of artesunate after single oral administration to rats

BACKGROUND: Artesunate is a commonly used antimalarial drug derived from artemisinin. It is rapidly converted to dihydroartemisinin. Little is known on this conversion in the GI tract and blood, and how this influences absorption. In order to study the absorption phase of the kinetics of artesunate...

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Bibliografiske detaljer
Main Authors: Olliaro, Piero L, Nair, Naren K, Sathasivam, Kathir, Mansor, Sharif M, Navaratnam, Vis
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC65525/
https://ncbi.nlm.nih.gov/pubmed/11835690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-1-12
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