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Pharmacokinetics of artesunate after single oral administration to rats

BACKGROUND: Artesunate is a commonly used antimalarial drug derived from artemisinin. It is rapidly converted to dihydroartemisinin. Little is known on this conversion in the GI tract and blood, and how this influences absorption. In order to study the absorption phase of the kinetics of artesunate...

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Hlavní autoři: Olliaro, Piero L, Nair, Naren K, Sathasivam, Kathir, Mansor, Sharif M, Navaratnam, Vis
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC65525/
https://ncbi.nlm.nih.gov/pubmed/11835690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-1-12
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