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Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration

SCOPE: Xanthohumol (XN), a dietary flavonoid found in hops, may have health protective actions against cardiovascular disease and type 2 diabetes. Yet, there are limited data on the pharmacokinetics (PK) of XN. This study provides PK parameters for XN and its major metabolites in rats. METHODS AND R...

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Main Authors: Legette, LeeCole, Ma, Lian, Reed, Ralph L., Miranda, Cristobal L., Christensen, J. Mark, Rodriguez-Proteau, Rosita, Stevens, Jan F.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401605/
https://ncbi.nlm.nih.gov/pubmed/22147307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201100554
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