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Telomerase reverse transcriptase ameliorates lung fibrosis by protecting alveolar epithelial cells against senescence
Mutations in the genes encoding telomerase reverse transcriptase (TERT) and telomerase's RNA components as well as shortened telomeres are risk factors for idiopathic pulmonary fibrosis, where repetitive injury to the alveolar epithelium is considered a key factor in pathogenesis. Given the imp...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6552422/ https://ncbi.nlm.nih.gov/pubmed/31000627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006615 |
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