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Telomerase reverse transcriptase ameliorates lung fibrosis by protecting alveolar epithelial cells against senescence
Mutations in the genes encoding telomerase reverse transcriptase (TERT) and telomerase's RNA components as well as shortened telomeres are risk factors for idiopathic pulmonary fibrosis, where repetitive injury to the alveolar epithelium is considered a key factor in pathogenesis. Given the imp...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6552422/ https://ncbi.nlm.nih.gov/pubmed/31000627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006615 |
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