FIZZ1-Induced Myofibroblast Transdifferentiation from Adipocytes and Its Potential Role in Dermal Fibrosis and Lipoatrophy

Subcutaneous lipoatrophy characteristically accompanies dermal fibrosis with de novo emergence of myofibroblasts such as in systemic sclerosis or scleroderma. Recently dermal adipocytes were shown to have the capacity to differentiate to myofibroblasts in an animal model. Transforming growth factor...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Martins, Vanessa, Gonzalez De Los Santos, Francina, Wu, Zhe, Capelozzi, Vera, Phan, Sem H., Liu, Tianju
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2015
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607756/
https://ncbi.nlm.nih.gov/pubmed/26261086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.06.005
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