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FIZZ1-Induced Myofibroblast Transdifferentiation from Adipocytes and Its Potential Role in Dermal Fibrosis and Lipoatrophy

Subcutaneous lipoatrophy characteristically accompanies dermal fibrosis with de novo emergence of myofibroblasts such as in systemic sclerosis or scleroderma. Recently dermal adipocytes were shown to have the capacity to differentiate to myofibroblasts in an animal model. Transforming growth factor...

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Podrobná bibliografie
Vydáno v:Am J Pathol
Hlavní autoři: Martins, Vanessa, Gonzalez De Los Santos, Francina, Wu, Zhe, Capelozzi, Vera, Phan, Sem H., Liu, Tianju
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607756/
https://ncbi.nlm.nih.gov/pubmed/26261086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.06.005
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