FIZZ1-Induced Myofibroblast Transdifferentiation from Adipocytes and Its Potential Role in Dermal Fibrosis and Lipoatrophy

Subcutaneous lipoatrophy characteristically accompanies dermal fibrosis with de novo emergence of myofibroblasts such as in systemic sclerosis or scleroderma. Recently dermal adipocytes were shown to have the capacity to differentiate to myofibroblasts in an animal model. Transforming growth factor...

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Dades bibliogràfiques
Publicat a:Am J Pathol
Autors principals: Martins, Vanessa, Gonzalez De Los Santos, Francina, Wu, Zhe, Capelozzi, Vera, Phan, Sem H., Liu, Tianju
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2015
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607756/
https://ncbi.nlm.nih.gov/pubmed/26261086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.06.005
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