FIZZ1-Induced Myofibroblast Transdifferentiation from Adipocytes and Its Potential Role in Dermal Fibrosis and Lipoatrophy

Subcutaneous lipoatrophy characteristically accompanies dermal fibrosis with de novo emergence of myofibroblasts such as in systemic sclerosis or scleroderma. Recently dermal adipocytes were shown to have the capacity to differentiate to myofibroblasts in an animal model. Transforming growth factor...

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Dettagli Bibliografici
Pubblicato in:Am J Pathol
Autori principali: Martins, Vanessa, Gonzalez De Los Santos, Francina, Wu, Zhe, Capelozzi, Vera, Phan, Sem H., Liu, Tianju
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2015
Soggetti:
Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607756/
https://ncbi.nlm.nih.gov/pubmed/26261086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.06.005
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