FIZZ1-Induced Myofibroblast Transdifferentiation from Adipocytes and Its Potential Role in Dermal Fibrosis and Lipoatrophy

Subcutaneous lipoatrophy characteristically accompanies dermal fibrosis with de novo emergence of myofibroblasts such as in systemic sclerosis or scleroderma. Recently dermal adipocytes were shown to have the capacity to differentiate to myofibroblasts in an animal model. Transforming growth factor...

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Foilsithe in:Am J Pathol
Main Authors: Martins, Vanessa, Gonzalez De Los Santos, Francina, Wu, Zhe, Capelozzi, Vera, Phan, Sem H., Liu, Tianju
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2015
Ábhair:
Regular Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607756/
https://ncbi.nlm.nih.gov/pubmed/26261086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.06.005
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