Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial

IMPORTANCE: Controlled studies have shown short-term efficacy of esketamine for treatment-resistant depression (TRD), but long-term effects remain to be established. OBJECTIVE: To assess the efficacy of esketamine nasal spray plus an oral antidepressant compared with an oral antidepressant plus plac...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:JAMA Psychiatry
Κύριοι συγγραφείς: Daly, Ella J., Trivedi, Madhukar H., Janik, Adam, Li, Honglan, Zhang, Yun, Li, Xiang, Lane, Rosanne, Lim, Pilar, Duca, Anna R., Hough, David, Thase, Michael E., Zajecka, John, Winokur, Andrew, Divacka, Ilona, Fagiolini, Andrea, Cubała, Wiesław J., Bitter, István, Blier, Pierre, Shelton, Richard C., Molero, Patricio, Manji, Husseini, Drevets, Wayne C., Singh, Jaskaran B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Medical Association 2019
Θέματα:
Original Investigation
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551577/
https://ncbi.nlm.nih.gov/pubmed/31166571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2019.1189
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