Temporal and sex differences in the role of BDNF/TrkB signaling in hyperalgesic priming in mice and rats

Brain-derived neurotrophic factor (BDNF) signaling through its cognate receptor, TrkB, is a well-known promoter of synaptic plasticity at nociceptive synapses in the dorsal horn of the spinal cord. Existing evidence suggests that BDNF/TrkB signaling in neuropathic pain is sex dependent. We tested th...

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Détails bibliographiques
Publié dans:Neurobiol Pain
Auteurs principaux: Moy, Jamie K., Szabo-Pardi, Thomas, Tillu, Dipti V., Megat, Salim, Pradhan, Grishma, Kume, Moeno, Asiedu, Marina N., Burton, Michael D., Dussor, Gregory, Price, Theodore J.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Original Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550116/
https://ncbi.nlm.nih.gov/pubmed/31194015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ynpai.2018.10.001
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