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The Role of Altered BDNF/TrkB Signaling in Amyotrophic Lateral Sclerosis

Brain derived neurotrophic factor (BDNF) is well recognized for its neuroprotective functions, via activation of its high affinity receptor, tropomysin related kinase B (TrkB). In addition, BDNF/TrkB neuroprotective functions can also be elicited indirectly via activation of adenosine 2A receptors (...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Pradhan, Jonu, Noakes, Peter G., Bellingham, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6700252/
https://ncbi.nlm.nih.gov/pubmed/31456666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00368
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