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Neurophysiological Mechanisms Underlying Cortical Hyper-Excitability in Amyotrophic Lateral Sclerosis: A Review

Amyotrophic lateral sclerosis (ALS) is a progressive neuromotor disease characterized by the loss of upper and lower motor neurons (MNs), resulting in muscle paralysis and death. Early cortical hyper-excitability is a common pathological process observed clinically and in animal disease models. Alth...

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Détails bibliographiques
Publié dans:Brain Sci
Auteurs principaux: Pradhan, Jonu, Bellingham, Mark C.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145013/
https://ncbi.nlm.nih.gov/pubmed/33925493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/brainsci11050549
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