Motor Areas Show Altered Dendritic Structure in an Amyotrophic Lateral Sclerosis Mouse Model

Objective: Motor neurons (MNs) die in amyotrophic lateral sclerosis (ALS), a clinically heterogeneous neurodegenerative disease of unknown etiology. In human or rodent studies, MN loss is preceded by increased excitability. As increased neuronal excitability correlates with structural changes in den...

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Pubblicato in:Front Neurosci
Autori principali: Fogarty, Matthew J., Mu, Erica W. H., Lavidis, Nickolas A., Noakes, Peter G., Bellingham, Mark C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672020/
https://ncbi.nlm.nih.gov/pubmed/29163013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00609
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