Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance

Prostate cancers harboring DNA repair gene alterations are particularly sensitive to PARP inhibitor treatment. We report a case of an advanced prostate cancer patient profiled within the NCT-MASTER (Molecularly Aided Stratification for Tumor Eradication Research) precision oncology program using nex...

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書誌詳細
出版年:Cold Spring Harb Mol Case Stud
主要な著者: Horak, Peter, Weischenfeldt, Joachim, von Amsberg, Gunhild, Beyer, Burkhard, Schütte, Andreas, Uhrig, Sebastian, Gieldon, Laura, Klink, Barbara, Feuerbach, Lars, Hübschmann, Daniel, Kreutzfeldt, Simon, Heining, Christoph, Maier, Sebastian, Hutter, Barbara, Penzel, Roland, Schlesner, Matthias, Eils, Roland, Sauter, Guido, Stenzinger, Albrecht, Brors, Benedikt, Schröck, Evelin, Glimm, Hanno, Fröhling, Stefan, Schlomm, Thorsten
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2019
主題:
Research Report
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549578/
https://ncbi.nlm.nih.gov/pubmed/30833416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a003657
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