Integrated Regulation of HuR by Translation Repression and Protein Degradation Determines Pulsatile Expression of p53 Under DNA Damage

Expression of tumor suppressor p53 is regulated at multiple levels, disruption of which often leads to cancer. We have adopted an approach combining computational systems modeling with experimental validation to elucidate the translation regulatory network that controls p53 expression post DNA damag...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:iScience
Main Authors: Guha, Abhishek, Ahuja, Deepika, Das Mandal, Sukhen, Parasar, Bibudha, Deyasi, Krishanu, Roy, Debadrita, Sharma, Vasundhara, Willard, Belinda, Ghosh, Anandamohan, Ray, Partho Sarothi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548907/
https://ncbi.nlm.nih.gov/pubmed/31103853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.05.002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados