Human Monocyte-Derived Dendritic Cells Produce Millimolar Concentrations of ROS in Phagosomes Per Second

Neutrophils kill ingested pathogens by the so-called oxidative burst, where reactive oxygen species (ROS) are produced in the lumen of phagosomes at very high rates (mM/s), although these rates can only be maintained for a short period (minutes). In contrast, dendritic cells produce ROS at much lowe...

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Udgivet i:Front Immunol
Main Authors: Paardekooper, Laurent M., Dingjan, Ilse, Linders, Peter T. A., Staal, Alexander H. J., Cristescu, Simona M., Verberk, Wilco C. E. P., van den Bogaart, Geert
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548834/
https://ncbi.nlm.nih.gov/pubmed/31191556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01216
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