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Oxygen in the tumor microenvironment: effects on dendritic cell function

Solid tumors grow at a high speed leading to insufficient blood supply to tumor cells. This makes the tumor hypoxic, resulting in the Warburg effect and an increased generation of reactive oxygen species (ROS). Hypoxia and ROS affect immune cells in the tumor micro-environment, thereby affecting the...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Paardekooper, Laurent M., Vos, Willemijn, van den Bogaart, Geert
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368231/
https://ncbi.nlm.nih.gov/pubmed/30783517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26608
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