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Oxygen in the tumor microenvironment: effects on dendritic cell function

Solid tumors grow at a high speed leading to insufficient blood supply to tumor cells. This makes the tumor hypoxic, resulting in the Warburg effect and an increased generation of reactive oxygen species (ROS). Hypoxia and ROS affect immune cells in the tumor micro-environment, thereby affecting the...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Paardekooper, Laurent M., Vos, Willemijn, van den Bogaart, Geert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368231/
https://ncbi.nlm.nih.gov/pubmed/30783517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26608
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