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Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation

Apoptosis can promote inflammation by triggering activation of the NLRP3 inflammasome (NLR family, pyrin domain containing 3). However, the molecular mechanisms regulating these processes are ill-defined. We recently reported that pannexin-1 is required to promote NLRP3 inflammasome assembly. We fur...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Demarco, Benjamin, Chen, Kaiwen W., Broz, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548479/
https://ncbi.nlm.nih.gov/pubmed/31211242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1610324
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