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Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation

Apoptosis can promote inflammation by triggering activation of the NLRP3 inflammasome (NLR family, pyrin domain containing 3). However, the molecular mechanisms regulating these processes are ill-defined. We recently reported that pannexin-1 is required to promote NLRP3 inflammasome assembly. We fur...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Oncol
Hauptverfasser: Demarco, Benjamin, Chen, Kaiwen W., Broz, Petr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548479/
https://ncbi.nlm.nih.gov/pubmed/31211242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1610324
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