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The Pannexin 1 Channel Activates the Inflammasome in Neurons and Astrocytes
The inflammasome is a multiprotein complex involved in innate immunity. Activation of the inflammasome causes the processing and release of the cytokines interleukins 1β and 18. In primary macrophages, potassium ion flux and the membrane channel pannexin 1 have been suggested to play roles in inflam...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709345/ https://ncbi.nlm.nih.gov/pubmed/19416975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.004804 |
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