The Pannexin 1 Channel Activates the Inflammasome in Neurons and Astrocytes

The inflammasome is a multiprotein complex involved in innate immunity. Activation of the inflammasome causes the processing and release of the cytokines interleukins 1β and 18. In primary macrophages, potassium ion flux and the membrane channel pannexin 1 have been suggested to play roles in inflam...

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Bibliografiset tiedot
Päätekijät: Silverman, William R., de Rivero Vaccari, Juan Pablo, Locovei, Silviu, Qiu, Feng, Carlsson, Steven K., Scemes, Eliana, Keane, Robert W., Dahl, Gerhard
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2009
Aiheet:
Membrane Transport, Structure, Function, and Biogenesis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709345/
https://ncbi.nlm.nih.gov/pubmed/19416975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.004804
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