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The Pannexin 1 Channel Activates the Inflammasome in Neurons and Astrocytes

The inflammasome is a multiprotein complex involved in innate immunity. Activation of the inflammasome causes the processing and release of the cytokines interleukins 1β and 18. In primary macrophages, potassium ion flux and the membrane channel pannexin 1 have been suggested to play roles in inflam...

詳細記述

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書誌詳細
主要な著者: Silverman, William R., de Rivero Vaccari, Juan Pablo, Locovei, Silviu, Qiu, Feng, Carlsson, Steven K., Scemes, Eliana, Keane, Robert W., Dahl, Gerhard
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709345/
https://ncbi.nlm.nih.gov/pubmed/19416975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.004804
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