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Probenecid, a gout remedy, inhibits pannexin 1 channels

Probenecid is a well-established drug for the treatment of gout and is thought to act on an organic anion transporter, thereby affecting uric acid excretion in the kidney by blocking urate reuptake. Probenecid also has been shown to affect ATP release, leading to the suggestion that ATP release invo...

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Detalhes bibliográficos
Main Authors: Silverman, William, Locovei, Silviu, Dahl, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544448/
https://ncbi.nlm.nih.gov/pubmed/18596212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00227.2008
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