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Probenecid, a gout remedy, inhibits pannexin 1 channels
Probenecid is a well-established drug for the treatment of gout and is thought to act on an organic anion transporter, thereby affecting uric acid excretion in the kidney by blocking urate reuptake. Probenecid also has been shown to affect ATP release, leading to the suggestion that ATP release invo...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2544448/ https://ncbi.nlm.nih.gov/pubmed/18596212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00227.2008 |
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