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A permeant regulating its permeation pore: inhibition of pannexin 1 channels by ATP

Pannexin 1 forms a large membrane channel that, based on its biophysical properties and its expression pattern, is a prime candidate to represent an ATP release channel. Pannexin 1 channel activity is potentially deleterious for cells as indicated by its involvement in the P2X7 death complex. Here w...

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Bibliografske podrobnosti
Main Authors: Qiu, Feng, Dahl, Gerhard
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643853/
https://ncbi.nlm.nih.gov/pubmed/18945939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00433.2008
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