The Pannexin 1 Channel Activates the Inflammasome in Neurons and Astrocytes

The inflammasome is a multiprotein complex involved in innate immunity. Activation of the inflammasome causes the processing and release of the cytokines interleukins 1β and 18. In primary macrophages, potassium ion flux and the membrane channel pannexin 1 have been suggested to play roles in inflam...

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Detalhes bibliográficos
Main Authors: Silverman, William R., de Rivero Vaccari, Juan Pablo, Locovei, Silviu, Qiu, Feng, Carlsson, Steven K., Scemes, Eliana, Keane, Robert W., Dahl, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709345/
https://ncbi.nlm.nih.gov/pubmed/19416975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.004804
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