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Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation

Apoptosis can promote inflammation by triggering activation of the NLRP3 inflammasome (NLR family, pyrin domain containing 3). However, the molecular mechanisms regulating these processes are ill-defined. We recently reported that pannexin-1 is required to promote NLRP3 inflammasome assembly. We fur...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Demarco, Benjamin, Chen, Kaiwen W., Broz, Petr
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548479/
https://ncbi.nlm.nih.gov/pubmed/31211242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1610324
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