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Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation

Apoptosis can promote inflammation by triggering activation of the NLRP3 inflammasome (NLR family, pyrin domain containing 3). However, the molecular mechanisms regulating these processes are ill-defined. We recently reported that pannexin-1 is required to promote NLRP3 inflammasome assembly. We fur...

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Vydáno v:Mol Cell Oncol
Hlavní autoři: Demarco, Benjamin, Chen, Kaiwen W., Broz, Petr
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548479/
https://ncbi.nlm.nih.gov/pubmed/31211242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1610324
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