Loss of PICH promotes chromosome instability and cell death in triple-negative breast cancer

Triple-negative breast cancer (TNBC), defined by the lack of expression of estrogen, progesterone, and ERBB2 receptors, has the worst prognosis of all breast cancers. It is difficult to treat owing to a lack of effective molecular targets. Here, we report that the growth of TNBC cells is exceptional...

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Vydáno v:Cell Death Dis
Hlavní autoři: Huang, Yan, Li, Wanjin, Yan, Weiwei, Wu, Jiaqi, Chen, Liang, Yao, Xiaohong, Gu, Feng, Lv, Luye, Zhao, Jiangman, Zhao, Ming, Xia, Tian, Han, Qiuying, Li, Teng, Ying, Xiaomin, Li, Tao, Xia, Qing, Li, Ailing, Zhang, Xuemin, Chen, Yuan, Zhou, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547724/
https://ncbi.nlm.nih.gov/pubmed/31160555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1662-6
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