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Topoisomerase IIα in Chromosome Instability and Personalized Cancer Therapy
Genome instability is a hallmark of cancer cells. Chromosome instability (CIN), which is often mutually exclusive from hypermutation genotypes, represents a distinct subtype of genome instability. Hypermutations in cancer cells are due to defects in DNA repair genes, but the cause of CIN is still el...
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| Publicado no: | Oncogene |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4404185/ https://ncbi.nlm.nih.gov/pubmed/25328138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.332 |
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