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Topoisomerase IIα in Chromosome Instability and Personalized Cancer Therapy

Genome instability is a hallmark of cancer cells. Chromosome instability (CIN), which is often mutually exclusive from hypermutation genotypes, represents a distinct subtype of genome instability. Hypermutations in cancer cells are due to defects in DNA repair genes, but the cause of CIN is still el...

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Bibliografski detalji
Izdano u:Oncogene
Glavni autori: Chen, Tao, Sun, Yan, Ji, Ping, Kopetz, Scott, Zhang, Wei
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404185/
https://ncbi.nlm.nih.gov/pubmed/25328138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.332
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