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Topoisomerase IIα is essential for maintenance of mitotic chromosome structure

Topoisomerase IIα (TOP2A) is a core component of mitotic chromosomes and important for establishing mitotic chromosome condensation. The primary roles of TOP2A in mitosis have been difficult to decipher due to its multiple functions across the cell cycle. To more precisely understand the role of TOP...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Nielsen, Christian F., Zhang, Tao, Barisic, Marin, Kalitsis, Paul, Hudson, Damien F.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275761/
https://ncbi.nlm.nih.gov/pubmed/32414923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2001760117
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