Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα

Mitotic chromosome formation involves a relatively minor condensation of the chromatin volume coupled with a dramatic reorganization into the characteristic “X” shape. Here we report results of a detailed morphological analysis, which revealed that chromokinesin KIF4 cooperated in a parallel pathway...

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Detalhes bibliográficos
Main Authors: Samejima, Kumiko, Samejima, Itaru, Vagnarelli, Paola, Ogawa, Hiromi, Vargiu, Giulia, Kelly, David A., de Lima Alves, Flavia, Kerr, Alastair, Green, Lydia C., Hudson, Damien F., Ohta, Shinya, Cooke, Carol A., Farr, Christine J., Rappsilber, Juri, Earnshaw, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514791/
https://ncbi.nlm.nih.gov/pubmed/23166350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201202155
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