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Rapid exchange of mammalian topoisomerase IIα at kinetochores and chromosome arms in mitosis
Astable cell line (GT2-LPk) derived from LLC-Pk was created in which endogenous DNA topoisomerase IIα (topoIIα) protein was downregulated and replaced by the expression of topoIIα fused with enhanced green fluorescent protein (EGFP–topoIIα). The EGFP–topoIIα faithfully mimicked the distribution of t...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173008/ https://ncbi.nlm.nih.gov/pubmed/12105179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200202053 |
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