Rapid exchange of mammalian topoisomerase IIα at kinetochores and chromosome arms in mitosis

Astable cell line (GT2-LPk) derived from LLC-Pk was created in which endogenous DNA topoisomerase IIα (topoIIα) protein was downregulated and replaced by the expression of topoIIα fused with enhanced green fluorescent protein (EGFP–topoIIα). The EGFP–topoIIα faithfully mimicked the distribution of t...

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Detaylı Bibliyografya
Asıl Yazarlar: Tavormina, Penny A., Côme, Marie-George, Hudson, Joanna R., Mo, Yin-Yuan, Beck, William T., Gorbsky, Gary J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2002
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173008/
https://ncbi.nlm.nih.gov/pubmed/12105179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200202053
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