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PICH and Cotargeted Plk1 Coordinately Maintain Prometaphase Chromosome Arm Architecture

To maintain genomic stability, chromosome architecture needs to be tightly regulated as chromosomes undergo condensation during prophase and separation during anaphase, but the mechanisms remain poorly understood. Here, we show that the Plk1-binding protein PICH and Plk1 kinase coordinately maintain...

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Detalhes bibliográficos
Main Authors: Kurasawa, Yasuhiro, Yu-Lee, Li-yuan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847523/
https://ncbi.nlm.nih.gov/pubmed/20130082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-11-0950
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