Loss of PICH promotes chromosome instability and cell death in triple-negative breast cancer

Triple-negative breast cancer (TNBC), defined by the lack of expression of estrogen, progesterone, and ERBB2 receptors, has the worst prognosis of all breast cancers. It is difficult to treat owing to a lack of effective molecular targets. Here, we report that the growth of TNBC cells is exceptional...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Huang, Yan, Li, Wanjin, Yan, Weiwei, Wu, Jiaqi, Chen, Liang, Yao, Xiaohong, Gu, Feng, Lv, Luye, Zhao, Jiangman, Zhao, Ming, Xia, Tian, Han, Qiuying, Li, Teng, Ying, Xiaomin, Li, Tao, Xia, Qing, Li, Ailing, Zhang, Xuemin, Chen, Yuan, Zhou, Tao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547724/
https://ncbi.nlm.nih.gov/pubmed/31160555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1662-6
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