Direct removal of RNA polymerase barriers to replication by accessory replicative helicases

Bacterial genome duplication and transcription require simultaneous access to the same DNA template. Conflicts between the replisome and transcription machinery can lead to interruption of DNA replication and loss of genome stability. Pausing, stalling and backtracking of transcribing RNA polymerase...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Hawkins, Michelle, Dimude, Juachi U, Howard, Jamieson A L, Smith, Abigail J, Dillingham, Mark S, Savery, Nigel J, Rudolph, Christian J, McGlynn, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
Onderwerpen:
Genome Integrity, Repair and Replication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547429/
https://ncbi.nlm.nih.gov/pubmed/30869136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz170
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