Direct removal of RNA polymerase barriers to replication by accessory replicative helicases

Bacterial genome duplication and transcription require simultaneous access to the same DNA template. Conflicts between the replisome and transcription machinery can lead to interruption of DNA replication and loss of genome stability. Pausing, stalling and backtracking of transcribing RNA polymerase...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hawkins, Michelle, Dimude, Juachi U, Howard, Jamieson A L, Smith, Abigail J, Dillingham, Mark S, Savery, Nigel J, Rudolph, Christian J, McGlynn, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547429/
https://ncbi.nlm.nih.gov/pubmed/30869136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz170
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